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Sanjeev Shukla,
Ph.D.
Instructor
Case Western Reserve University
11100 Euclid Avenue, Cleveland, OH 44106-4931
Phone: 216-368-0216, Fax: 216-368-0213
sanjeev.shukla@case.edu
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Professional Experience
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 2008-
Instructor, Department of Urology, Case School of Medicine |
| 2005- Senior
Research Associate, Department of Urology, Case School of Medicine |
| 2002- Research
Associate, Department of Urology,
Case School of Medicine |
Training
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| Ph.D.:
1992 Kanpur University, India |
| Postdoctoral
Fellowship: 1998-2002, King George's Medical College, India |
| Postdoctoral
Fellowship: 1993-97 Industrial Toxicology Research Center, India |
Interests
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| Find specific biomarker(s) for prostate cancer detection,
Mechanistic evaluation of prostate carcinogenesis, Translational studies with
naturally occurring and/or synthetic compounds to prevent prostate cancer |
Recent Publications
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Shukla S, MacLennan GT, Fu P, Patel J, Marengo SR, Resnick MI and Gupta S:
Nuclear factor-kappaB/p65 (Rel A) is constitutively activated in human prostate
adenocarcinoma and correlates with disease progression. Neoplasia, 6: 390-400,
2004
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Shukla S, Mishra A, Fu P, MacLennan GT, Resnick MI, and Sanjay Gupta:
Up-regulation of insulin-like growth factor binding protein-3 by apigenin leads
to growth inhibition and apoptosis of 22Rv1 xenograft in athymic nude mice.
FASEB J. 19:2042-4, 2005
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Shukla S and Gupta S: Molecular targets for apigenin-induced cell cycle arrest
and apoptosis in prostate cancer cell xenograft. Molecular Cancer Therapeutics,
5:843-52, 2006
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Shukla S, Maclennan GT, Flask CA, Fu P, Mishra A, Resnick MI, Gupta S. Blockade
of {beta}-Catenin Signaling by Plant Flavonoid Apigenin Suppresses Prostate
Carcinogenesis in TRAMP Mice. Cancer Res. 67:6925-35, 2007
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Shukla S, Gupta S. Apigenin-induced prostate cancer cell death is initiated by
reactive oxygen species and p53 activation. Free Radical Biol. Med. 44:1833-45.
2008
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